
MacroGenics reports 25% response in clear cell gynecologic cancer trial
Four of 16 evaluable patients responded to lorigerlimab as the company enrols a lower-dose cohort after significant treatment-related toxicity.

Separate mine, plant, water and infrastructure approvals remain outstanding ahead of a targeted production decision in early 2027.

Four of 16 evaluable patients responded to lorigerlimab as the company enrols a lower-dose cohort after significant treatment-related toxicity.

Ocean Partners would own about 6.5 per cent before warrant exercise, with proceeds supporting Steller exploration and a study in the first half of 2027.
The program will test domestic carbon composites for high-temperature defence systems, but payment terms and a testing deadline remain undisclosed.
RESOLVE will test symptom recovery and hospitalization in high-risk adults, starting with at least 200 patients in its Phase 2b portion.

The intercept lies 60 metres up-dip from a historical hole inside the inferred resource, supporting plans to upgrade portions to indicated.

The 541-patient DYNASTY-Breast02 trial met its primary endpoint, but the partners say potential patient benefit is limited.

Three new holes support mineralisation to at least 300 metres depth, with more than 32 holes still awaiting complete assays.

Pumitamig plus docetaxel showed early activity after immunotherapy and chemotherapy, but the Phase 2 study had no control arm.
Ivonescimab plus chemotherapy extended median survival to 14.9 months in a China-only study, with a separate U.S. trial planned.
Google will fund flexible household and business resources in PJM, but the companies disclose no price or delivery schedule.
A 401-infant presentation compared immune responses and safety with Prevnar 20; the company has not dated its pediatric Phase 3 readout.
Proprietary bitcoin holdings remained at zero as of Oct. 23, while the update omitted sale prices and cash proceeds.
The California services acquisition would close in two stages, with cash, a seller note and an earnout subject to separate utility approvals.
Crews are assessing two undrilled occurrences and the corridor between them, with initial results expected in early 2027.
An independent board will review ReMEDy2 in Q1 2027 and may resize the study to as many as 728 participants or stop it for futility.
Gold, silver, uranium, lithium, copper and rare earths: the producers, the developers and the projects behind them.
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USW Local 7619 represents about 1,200 workers at the B.C. copper operation, whose production loss has not been quantified.
Medical and pharmaceutical developments, psychedelics, and the research and safety questions around them.
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Severe or worse treatment-related adverse events affected 72.1 per cent across expansion cohorts; FDA talks are planned for 2027.
Technology, computing, crypto and cannabis, and the listed companies moving in them.
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Directors retain discretion over the ratio for common and exchangeable shares, with no effective date set in the voting disclosure.
A US$1.2 billion agreement spans 2026 to 2030, while a one-time tariff refund lifted the September quarter’s reported earnings.
Uranium, lithium, oil and gas, hydrogen and the grid: the fuels and the companies behind them.
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The delayed draw facility starts with US$171 million borrowed and a 180-day maturity, with an extension tied to supply agreements and lender consent.

The National Wealth Fund is providing £12.2 million, with admission targeted for Nov. 12 subject to shareholder approval.

An initial study is estimated at six months; NANO disclosed no retainer amount, fabrication price or component delivery date.
Licensed producers, retail, policy, and the psychedelics companies moving through the clinic.
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The capsules are intended for three programs, including a Canadian Phase 3 PTSD trial of up to 100 people expected to begin in 2027.

The province estimates illegal retailers take 30 per cent of cannabis sales and proposes inspection, seizure and penalty powers for the AGCO.

The bid offers US$1 in cash plus 0.4013 Curaleaf shares for each Aurora share, with a Dec. 4 tender deadline.

Cash earnouts tied to 2026 and 2027 earnings add to the base price for a grower supplying nearly all 69 shops in the Dutch pilot.